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The JAK-STAT (signal transducer and activator of transcription) pathway plays a key role in the signaling of many cytokines and growth factors and is involved in cellular proliferation
MK-8033 Y2940680 The JAK-STAT (signal transducer andMK8033 is a selective small molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK 8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre and post treatment biopsies to evaluate for relevant molecular signatures. Product information CAS Number: 1001917 37 8 Molecular Weight: 471. 53 Formula: C25H21N5O3S Synonym: MK 8033 MK 8033 MK8033 Chemical Name: 1 [5 (1 methyl 1H pyrazol 4 yl) 2
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