Black can pluck them from you hand, white can make casting spells awkward while the best red or green can do to curtail casting is to attack the mana base
A broader card pool would allow you, among other things, to streamline the deck and make it faster and more consistent (Bishop of Wings, Esper Sentinel, Mother of Runes, Selfless Spirit, Starnheim Aspirant, etc.)
This Commander deck set includes: 99-card deck, 1 foil Commander card, 10 double-sided tokens, life wheel, and deck box
That said, getting three poison on your opponent is significant set up, and the baseline card is pretty bad If you can play him early, he can get a few poison on your opponent so your corrupted cards get better, and if you get him late, he can function as a really obnoxious way to protect your other creatures from removal or make them unblockable
Here's how it works: You're the sled