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AK-1 oacetamido-C-PEG3-C3-NHBoc and as ester derivative (GSK-J5)

SKU: 25984598156

4.3
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Description

and as ester derivative (GSK-J5) in cells

Formula: C25H32N8O

SB-525334 (1 microM) blocked TGF-beta1-induced phosphorylation and nuclear translocation of Smad2/3 in renal proximal tubule cells and inhibited TGF-beta1-induced increases in plasminogen activator inhibitor-1 (PAI-1) and procollagen alpha1(I) mRNA expression in A498 renal epithelial carcinoma cells

Manidipine

InChi: InChI=1S/C12H9Cl2NO4/c13-5-3-7(14)10-6(1-2-9(16)17)11(12(18)19)15-8(10)4-5/h3-4

AK-1 oacetamido-C-PEG3-C3-NHBoc and as ester derivative (GSK-J5)AK 1 is a potent, specific and cell permeable SIRT2 inhibitor, with an IC50 of 12. 5 M. Product information CAS Number: 330461 64 8 Molecular Weight: 403. 45 Formula: C19H21N3O5S Chemical Name: 3 (azepane 1 sulfonyl) N (3 nitrophenyl)benzamide Smiles: [O ][N+](=O)C1=CC(=CC=C1)NC(=O)C1C=C(C=CC=1)S(=O)(=O)N1CCCCCC1 InChiKey: HAYBKCHPEBZNGW UHFFFAOYSA N InChi: InChI=1S C19H21N3O5S c23 19(20 16 8 6 9 17(14 16)22(24)25)15 7 5 10 18(13 15)28(26,27)21 11 3 1

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