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MS402 Catalog No.:M25614-C PF-4800567 (100 mg/kg

SKU: 37902723922

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Description

PF-4800567 (100 mg/kg

CAS Number: 84687-42-3

InChiKey: UHEIPGJSFDAPIC-NENXIMLWSA-N

Chemical Name: (3S)-3-[(2S)-2-[(2S)-2-(3-{[(tert-butoxy)carbonyl]amino}propanamido)-3-(1H-indol-3-yl)propanamido]-4-(methylsulfanyl)butanamido]-3-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}propanoic acid

76(4):847-9

MS402 Catalog No.:M25614-C PF-4800567 (100 mg/kgMS402 is a BD1 selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice. Product information CAS Number: 1672684 68 2 Molecular Weight: 370. 83 Formula: C20H19ClN2O3 Chemical Name: 3 chloro N (4 methoxyphenyl) 4 [(2 methyl 3 oxocyclopent 1 en 1 yl)amino]benzamide

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