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assays and selectively blocks proliferation of AML cell lines harboring FLT3-ITD mutations
Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression
It is used either by injection into a muscle or into a vein
da Silva CA
26)/t19-/m1/s1
L-2-Hydroxyglutaric acid Catalog No.:M15026-2 assays and selectively blocks proliferationL 2 Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L 2 Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation. L 2 Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi CK) activity with Km and Ki of 2. 52 mM and 11. 13 mM, respectively. Product information CAS Number: 13095 48 2 Molecular Weight: 148. 11 Formula: C5H8O5 Chemical Name: (2S) 2
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