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5 hours) completely depletes both monomeric and dimeric STAT3 protein in MOLM-16 cells
these biochemical data support a mechanism of action of molnupiravir that is primarily based on RNA mutagenesis mediated via the template strand
O'Donnell EK
Campbell ST
XL228 is a protein kinase inhibitor with IC50 of 5 nM
BAY-293 orph 5 hours) completely depletes bothBAY 293 selectively inhibits the KRAS SOS1 interaction with an IC50 of 21 nM. Product information CAS Number: 2244904 70 7 Molecular Weight: 448. 58 Formula: C25H28N4O2S Chemical Name: 6,7 dimethoxy 2 methyl N [1 (4 {2 [(methylamino)methyl]phenyl}thiophen 2 yl)ethyl]quinazolin 4 amine Smiles: CC1N=C(NC(C)C2=CC(=CS2)C2=CC=CC=C2CNC)C2=CC(OC)=C(C=C2N=1)OC InChiKey: WEGLOYDTDILXDA UHFFFAOYSA N InChi: InChI=1S C25H28N4O2S c1 15(24 10 18(14 32 24)19 9 7 6 8
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