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GDC-0834 - CAS# 1133432-49-1 Catalog No.:M10101-10 6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl]-N-cyclohexyl-6-methylpiperidine-3-carboxamide

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Description

6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl]-N-cyclohexyl-6-methylpiperidine-3-carboxamide

but more potent synthetic analogs are being investigated as potential drugs

including flow cytometers

suppresses osteoclast formation and bone resorption through down-regulation of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand (RANKL)-induced c-Fos and nuclear factor of activated T cells (NFAT) c1 expression

PubMed Central PMCID: PMC6003652

GDC-0834 - CAS# 1133432-49-1 Catalog No.:M10101-10 6R)-1-[6-(3-amino-1H-indazol-6-yl)-2-(methylamino)pyrimidin-4-yl]-N-cyclohexyl-6-methylpiperidine-3-carboxamideGDC 0834 is an anti arthritis agent that inhibits Bruton's tyrosine kinase. Product information CAS Number: 1133432 49 1 Molecular Weight: 596. 74 Formula: C33H36N6O3S Synonym: GDC 0834 GDC0834 Chemical Name: N {3 [6 ({4 [(2R) 1,4 dimethyl 3 oxopiperazin 2 yl]phenyl}amino) 4 methyl 5 oxo 4,5 dihydropyrazin 2 yl] 2 methylphenyl} 4,5,6,7 tetrahydro 1 benzothiophene 2 carboxamide Smiles:

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